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Rabbit anti-Human LPHN2 Polyclonal Antibody

The antibody against ADGRL2 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human Latrophilin-2. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on IHC, IF, ELISA.

ADC-35816A

The antibody against ADGRL2 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human Latrophilin-2. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on IHC, IF, ELISA.

$167.00

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Specifications


Cat.No ADC-35816A ClonalityPolyclonal
Host SpeciesRabbitTarget NameADGRL2
FormLiquidSpecies ReactivityHuman, Mouse, Rat
IsotypeIgGStorage Buffer0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol
Purification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.ConjugateNon-conjugated
ApplicationELISA, IF, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from the Internal region of Human Latrophilin-2.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDO95490
Background Information
  • Uniprot Id

    O95490

  • Target Species

    Human

  • Target Name

    ADGRL2

  • Target Full Name

    Adhesion G protein-coupled receptor L2

  • Target Function

    Calcium-independent receptor of low affinity for alpha-latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis.

  • Target Subcellular Location

    Membrane; Multi-pass membrane protein.

  • Target Protein Families

    G-protein coupled receptor 2 family, Adhesion G-protein coupled receptor (ADGR) subfamily

  • Target Tissue Specificity

    Expressed very widely in all normal tissues tested. Expression is variable in tumor cell lines, apparently elevated in some lines and absent or markedly reduced in others.

  • Target Synonyms

    Adgrl2; Adhesion G protein-coupled receptor L2; AGRL2_HUMAN; Calcium-independent alpha-latrotoxin receptor 2; CIRL-2; CL2; KIAA0786; Latrophilin 1; Latrophilin 2; Latrophilin homolog 1; latrophilin homolog 2; Latrophilin-2; LEC1; Lectomedin-1; LPH2; LPHH1; LPHN2_HUMAN

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