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Rabbit anti-Human LSM6 Polyclonal Antibody

The antibody against LSM6 was raised in rabbit using the Recombinant Human U6 snRNA-associated Sm-like protein LSm6 protein (1-80AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

ADC-24528A

The antibody against LSM6 was raised in rabbit using the Recombinant Human U6 snRNA-associated Sm-like protein LSm6 protein (1-80AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

$299.00

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Specifications


Cat.No ADC-24528A ClonalityPolyclonal
Host SpeciesRabbitTarget NameLSM6
Target SynonymsLSM6U6 snRNA-associated Sm-like protein LSm6 antibodyFormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4Purification Method>95%, Protein G purified
ConjugateNon-conjugatedApplicationELISA
StorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human U6 snRNA-associated Sm-like protein LSm6 protein (1-80AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP62312
Background Information
  • Uniprot Id

    P62312

  • Target Species

    Human

  • Target Name

    LSM6

  • Target Full Name

    U6 snRNA-associated Sm-like protein LSm6

  • Target Function

    Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway (Probable).

  • Target Subcellular Location

    Cytoplasm. Nucleus.

  • Target Protein Families

    SnRNP Sm proteins family, SmF/LSm6 subfamily

  • Target Synonyms

    LSM6U6 snRNA-associated Sm-like protein LSm6

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