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Rabbit anti-Human LSM8 Polyclonal Antibody

The antibody against LSM8 was raised in rabbit using the Recombinant Human U6 snRNA-associated Sm-like protein LSm8 protein (2-96AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.

ADC-04317A

The antibody against LSM8 was raised in rabbit using the Recombinant Human U6 snRNA-associated Sm-like protein LSm8 protein (2-96AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.

$299.00

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Specifications


Cat.No ADC-04317A ClonalityPolyclonal
Host SpeciesRabbitTarget NameLSM8
Target SynonymsLSM8U6 snRNA-associated Sm-like protein LSm8 antibodyFormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4Purification Method>95%, Protein G purified
ConjugateNon-conjugatedApplicationELISA, IHC
StorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human U6 snRNA-associated Sm-like protein LSm8 protein (2-96AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDO95777
Background Information
  • Uniprot Id

    O95777

  • Target Species

    Human

  • Target Name

    LSM8

  • Target Full Name

    U6 snRNA-associated Sm-like protein LSm8

  • Target Function

    Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    SnRNP Sm proteins family

  • Target Synonyms

    LSM8U6 snRNA-associated Sm-like protein LSm8

  • Target Background

    This gene encodes a member of the like-Sm family of proteins. The encoded protein consists of a closed barrel shape, made up of five anti-parallel beta strands and an alpha helix. This protein partners with six paralogs to form a heteroheptameric ring which transiently binds U6 small nuclear RNAs and is involved in the general maturation of RNA in the nucleus.

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