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Rabbit anti-Human LTB4R Polyclonal Antibody

The antibody against LTB4R was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 253-352 of human LTB4R (NP_001137391.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-05302A

The antibody against LTB4R was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 253-352 of human LTB4R (NP_001137391.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-05302A ClonalityPolyclonal
Host SpeciesRabbitTarget NameLTB4R
Target SynonymsBLT1; BLTR; P2Y7; GPR16; LTBR1; P2RY7; CMKRL1; LTB4R1; LTB4RFormLiquid
Species ReactivityMouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse skeletal muscle, Rat skeletal muscleApplicationELISA, WB

Immunogen Information


Immunogen DescriptionA synthetic peptide corresponding to a sequence within amino acids 253-352 of human LTB4R (NP_001137391.1).Target SpeciesHuman
Immunogen SequenceAAGLGLVGKRLSLARNVLIALAFLSSSVNPVLYACAGGGLLRSAGVGFVAKLLEGTGSEASSTRRGGSLGQTARSGPAALEPGPSESLTASSPLKLNELNUniprot IDQ15722
Background Information
  • Uniprot Id

    Q15722

  • Target Species

    Human

  • Target Name

    LTB4R

  • Target Full Name

    Leukotriene B4 receptor 1

  • Target Function

    Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.

  • Target Subcellular Location

    Cell membrane; Multi-pass membrane protein.

  • Target Protein Families

    G-protein coupled receptor 1 family

  • Target Tissue Specificity

    Expressed at highest levels in heart, skeletal muscle and at lower levels in brain and liver. High level of expression in lymphoid tissues.

  • Target Synonyms

    LTB4R; BLT; BLT1; BLTR; CMKRL1; GPR16; P2RY7; Leukotriene B4 receptor 1; LTB4-R 1; LTB4-R1; Chemoattractant receptor-like 1; G-protein coupled receptor 16; P2Y purinoceptor 7; P2Y7

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