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The antibody against LUM was raised in rabbit using the Recombinant Human Lumican protein (19-338AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against LUM was raised in rabbit using the Recombinant Human Lumican protein (19-338AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
Immunohistochemistry of paraffin-embedded human lung cancer using LUM Antibody at dilution of 1:100
| Cat.No | ADC-17607A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | Lum |
| Target Synonyms | Keratan sulfate proteoglycan lumican antibody; KSPG lumican antibody; LDC antibody; LUM antibody; LUM_HUMAN antibody; Lumican antibody; Lumican precursor antibody; SLRR2D antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Lumican protein (19-338AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P51884 |
Uniprot Id
P51884
Target Species
Human
Target Name
LUM
Target Full Name
Lumican
Target Subcellular Location
Secreted, extracellular space, extracellular matrix.
Target Protein Families
Small leucine-rich proteoglycan (SLRP) family, SLRP class II subfamily
Target Tissue Specificity
Cornea and other tissues.
Target Synonyms
Keratan sulfate proteoglycan lumican; KSPG lumican; LDC; LUM; LUM_HUMAN; Lumican; Lumican precursor; SLRR2D
Target Background
This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, the protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. Lumican is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair.
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