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Rabbit anti-Human LY75 Polyclonal Antibody

The antibody against LY75 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human CD205. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.

ADC-35124A

The antibody against LY75 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human CD205. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.

$167.00

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Specifications


Cat.No ADC-35124A ClonalityPolyclonal
Host SpeciesRabbitTarget NameLY75
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol
Purification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.ConjugateNon-conjugated
ApplicationELISA, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from the Internal region of Human CD205.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDO60449
Background Information
  • Uniprot Id

    O60449

  • Target Species

    Human

  • Target Name

    LY75

  • Target Full Name

    Lymphocyte antigen 75

  • Target Function

    Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment. Causes reduced proliferation of B-lymphocytes.

  • Target Subcellular Location

    Membrane; Single-pass type I membrane protein.

  • Target Tissue Specificity

    Expressed in spleen, thymus, colon and peripheral blood lymphocytes. Detected in myeloid and B-lymphoid cell lines. Isoform 2 and isoform 3 are expressed in malignant Hodgkin lymphoma cells called Hodgkin and Reed-Sternberg (HRS) cells.

  • Target Synonyms

    C-type lectin domain family 13 member B; CD 205; CD205; CD205 antigen; CLEC 13B; CLEC13B; DEC 205; DEC-205; DEC205; gp200; gp200 MR6; gp200-MR6; LY 75; Ly-75; LY75; LY75_HUMAN; Lymphocyte antigen 75; Renal Cell Carcinoma (gp200)

  • Target Background

    Predicted to enable signaling receptor activity. Predicted to be involved in immune response and inflammatory response. Located in extracellular exosome.

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