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The antibody against MAGEC2 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human MAGE-C2. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
The antibody against MAGEC2 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human MAGE-C2. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
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Western Blot analysis of 293 cells using MAGE-C2 Polyclonal Antibody
Western Blot analysis of NIH-3T3 HuvEc Jurkat cells using MAGE-C2 Polyclonal Antibody2
Western blot analysis of mouse-brain HELA KB SH-SY5Y 293T 3T3 lysis using MAGE-C2 antibody.3
| Cat.No | ADC-38290A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MAGEC2 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human MAGE-C2. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9UBF1 |
Uniprot Id
Q9UBF1
Target Species
Human
Target Name
MAGEC2
Target Full Name
Melanoma-associated antigen C2
Target Function
Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. In vitro enhances ubiquitin ligase activity of TRIM28 and stimulates p53/TP53 ubiquitination in presence of Ubl-conjugating enzyme UBE2H leading to p53/TP53 degradation. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzymes (E2) at the E3:substrate complex.
Target Subcellular Location
Cytoplasm. Nucleus. Note=Nuclear in germ cells. Cytoplasmic in well-differentiated hepatocellular carcinoma, nuclear in moderately- and poorly-differentiated hepatocellular carcinoma.
Target Tissue Specificity
Not expressed in normal tissues, except in germ cells in the seminiferous tubules and in Purkinje cells of the cerebellum. Expressed in various tumors, including melanoma, lymphoma, as well as pancreatic cancer, mammary gland cancer, non-small cell lung c
Target Research Area
Others
Target Synonyms
Cancer testis antigen 10; Cancer/testis antigen 10; CT10; HCA587; Hepatocellular cancer antigen 587; Hepatocellular carcinoma associated antigen 587; Hepatocellular carcinoma-associated antigen 587; MAGC2_HUMAN; MAGE C2 antigen; MAGE E1 antigen; MAGE family member C2; MAGE-C2 antigen; MAGE-E1 antigen; MAGEC2; Melanoma antigen family C 2; Melanoma antigen family C2; Melanoma antigen family E 1 cancer/testis specific; Melanoma associated antigen C2; Melanoma-associated antigen C2; MGC13377
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