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The antibody against MAGI2 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human MAGI-2. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.
The antibody against MAGI2 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human MAGI-2. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.
$167.00
| Cat.No | ADC-33221A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MAGI2 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human MAGI-2. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q86UL8 |
Uniprot Id
Q86UL8
Target Species
Human
Target Name
MAGI2
Target Full Name
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2
Target Function
Seems to act as scaffold molecule at synaptic junctions by assembling neurotransmitter receptors and cell adhesion proteins. May play a role in regulating activin-mediated signaling in neuronal cells. Enhances the ability of PTEN to suppress AKT1 activation. Plays a role in nerve growth factor (NGF)-induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth.
Target Involvement
Nephrotic syndrome 15 (NPHS15)
Target Subcellular Location
Cytoplasm. Late endosome. Cell junction, synapse, synaptosome. Cell membrane; Peripheral membrane protein.
Target Protein Families
MAGUK family
Target Tissue Specificity
Specifically expressed in brain.
Target Synonyms
Activin receptor interacting protein 1; Acvri1 ; Acvrinp1; ACVRIP1; AIP 1; Aip-1; ARIP1; Atrophin 1 interacting protein 1; Atrophin 1 interacting protein A; Atrophin-1-interacting protein 1; Atrophin-1-interacting protein A; KIAA0705; MAGI-2; MAGI2; MAGI2_HUMAN; Membrane associated guanylate kinase 2; Membrane associated guanylate kinase inverted 2; Membrane associated guanylate kinase WW and PDZ domain containing 2; Membrane associated guanylate kinase WW and PDZ domain containing protein 2; Membrane-associated guanylate kinase; Membrane-associated guanylate kinase inverted 2; S SCAM ; SSCAM; WW and PDZ domain-containing protein 2
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