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Rabbit anti-Human MAGI2 Polyclonal Antibody

The antibody against MAGI2 was raised in rabbit using the Synthesized peptide derived from internal of Human MAGI2. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.

ADC-41904A

The antibody against MAGI2 was raised in rabbit using the Synthesized peptide derived from internal of Human MAGI2. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.

$297.00

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Specifications


Cat.No ADC-41904A ClonalityPolyclonal
Host SpeciesRabbitTarget NameMAGI2
FormLiquidSpecies ReactivityHuman, Mouse, Rat
Storage BufferPH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+)Purification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ApplicationELISA, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from internal of Human MAGI2.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ86UL8
Background Information
  • Uniprot Id

    Q86UL8

  • Target Species

    Human

  • Target Name

    MAGI2

  • Target Full Name

    Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2

  • Target Function

    Seems to act as scaffold molecule at synaptic junctions by assembling neurotransmitter receptors and cell adhesion proteins. May play a role in regulating activin-mediated signaling in neuronal cells. Enhances the ability of PTEN to suppress AKT1 activation. Plays a role in nerve growth factor (NGF)-induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth.

  • Target Involvement

    Nephrotic syndrome 15 (NPHS15)

  • Target Subcellular Location

    Cytoplasm. Late endosome. Cell junction, synapse, synaptosome. Cell membrane; Peripheral membrane protein.

  • Target Protein Families

    MAGUK family

  • Target Tissue Specificity

    Specifically expressed in brain.

  • Target Synonyms

    Activin receptor interacting protein 1; Acvri1 ; Acvrinp1; ACVRIP1; AIP 1; Aip-1; ARIP1; Atrophin 1 interacting protein 1; Atrophin 1 interacting protein A; Atrophin-1-interacting protein 1; Atrophin-1-interacting protein A; KIAA0705; MAGI-2; MAGI2; MAGI2_HUMAN; Membrane associated guanylate kinase 2; Membrane associated guanylate kinase inverted 2; Membrane associated guanylate kinase WW and PDZ domain containing 2; Membrane associated guanylate kinase WW and PDZ domain containing protein 2; Membrane-associated guanylate kinase; Membrane-associated guanylate kinase inverted 2; S SCAM ; SSCAM; WW and PDZ domain-containing protein 2

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