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The antibody against MAN2A1 was raised in rabbit using the Recombinant Human Alpha-mannosidase 2 protein (31-181AA) as the immunogen. This antibody exists as a hrp conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against MAN2A1 was raised in rabbit using the Recombinant Human Alpha-mannosidase 2 protein (31-181AA) as the immunogen. This antibody exists as a hrp conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-10477A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MAN2A1 |
| Target Synonyms | 3 1, 6 alpha mannosidase antibody; Mannosyl-oligosaccharide 1 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | HRP conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Alpha-mannosidase 2 protein (31-181AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q16706 |
Uniprot Id
Q16706
Target Species
Human
Target Name
MAN2A1
Target Full Name
Alpha-mannosidase 2
Target Function
Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway.
Target Subcellular Location
Golgi apparatus membrane; Single-pass type II membrane protein.
Target Protein Families
Glycosyl hydrolase 38 family
Target Synonyms
3-1; 6-alpha-mannosidase; Alpha mannosidase 2; alpha Mannosidase II; Alpha-mannosidase 2; AMAN II; Golgi alpha mannosidase II; Golgi alpha-mannosidase II; Golgi integral membrane protein 7; GOLIM7; MA2A1_HUMAN; MAN II; Man2a1; MANA 2; MANA2; MANII; Mann II; Mannosidase alpha class 2A member 1; Mannosidase Two; Mannosidase; alpha type II; Mannosidase; alpha; II; Mannosyl oligosaccharide 1 3 1 6 alpha mannosidase; Mannosyl oligosaccharide 1,3 1,6 alpha mannosidase; Mannosyl-oligosaccharide 1
Target Background
This gene encodes a glycosyl hydrolase that localizes to the Golgi and catalyzes the final hydrolytic step in the asparagine-linked oligosaccharide (N-glycan) maturation pathway. Mutations in the mouse homolog of this gene have been shown to cause a systemic autoimmune disease similar to human systemic lupus erythematosus.
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