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Rabbit anti-Human MAOA Polyclonal Antibody

The antibody against MAOA was raised in rabbit using the Synthesized peptide derived from the Internal region of Human MAO-A. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.

ADC-38288A

The antibody against MAOA was raised in rabbit using the Synthesized peptide derived from the Internal region of Human MAO-A. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.

$167.00

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Specifications


Cat.No ADC-38288A ClonalityPolyclonal
Host SpeciesRabbitTarget NameMAOA
Target SynonymsMAOA; Amine oxidase [flavin-containing] A; Monoamine oxidase type A; MAO-AFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerolPurification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ConjugateNon-conjugatedApplicationELISA, IHC, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from the Internal region of Human MAO-A.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP21397
Background Information
  • Uniprot Id

    P21397

  • Target Species

    Human

  • Target Name

    MAOA

  • Target Full Name

    Amine oxidase [flavin-containing] A

  • Target Function

    Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine.

  • Target Involvement

    Brunner syndrome (BRNRS)

  • Target Subcellular Location

    Mitochondrion outer membrane; Single-pass type IV membrane protein; Cytoplasmic side.

  • Target Protein Families

    Flavin monoamine oxidase family

  • Target Tissue Specificity

    Heart, liver, duodenum, blood vessels and kidney.

  • Target Synonyms

    MAOA; Amine oxidase [flavin-containing] A; Monoamine oxidase type A; MAO-A

  • Target Background

    This gene is one of two neighboring gene family members that encode mitochondrial enzymes which catalyze the oxidative deamination of amines, such as dopamine, norepinephrine, and serotonin. Mutation of this gene results in Brunner syndrome. This gene has also been associated with a variety of other psychiatric disorders, including antisocial behavior. Alternatively spliced transcript variants encoding multiple isoforms have been observed.

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