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The antibody against MAP1LC3B2 was raised in rabbit using the Recombinant Human Microtubule-associated proteins 1A/1B light chain 3 beta 2 protein (1-47AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against MAP1LC3B2 was raised in rabbit using the Recombinant Human Microtubule-associated proteins 1A/1B light chain 3 beta 2 protein (1-47AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
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| Cat.No | ADC-14671A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MAP1LC3B2 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Biotin conjugated |
| Application | ELISA | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Microtubule-associated proteins 1A/1B light chain 3 beta 2 protein (1-47AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | A6NCE7 |
Uniprot Id
A6NCE7
Target Species
Human
Target Name
MAP1LC3B2
Target Full Name
Microtubule-associated protein 1 light chain 3 beta 2
Target Function
Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.
Target Subcellular Location
Cytoplasm, cytoskeleton. Endomembrane system; Lipid-anchor. Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor.
Target Protein Families
ATG8 family
Target Synonyms
ATG8G; MAP1LC3B2; Microtubule associated protein 1 light chain 3 beta 2; Microtubule associated proteins 1A/1B light chain 3B like protein; Microtubule-associated proteins 1A/1B light chain 3 beta 2; Microtubule-associated proteins 1A/1B light chain 3B-like; MP3B2_HUMAN
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