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The antibody against MAP4K3 was raised in rabbit using the Recombinant Human Mitogen-activated protein kinase kinase kinase kinase 3 protein (755-894AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against MAP4K3 was raised in rabbit using the Recombinant Human Mitogen-activated protein kinase kinase kinase kinase 3 protein (755-894AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using MAP4K3 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human heart tissue using MAP4K3 Antibody at dilution of 1:1002
| Cat.No | ADC-17021A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MAP4K3 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Mitogen-activated protein kinase kinase kinase kinase 3 protein (755-894AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8IVH8 |
Uniprot Id
Q8IVH8
Target Species
Human
Target Name
MAP4K3
Target Full Name
Mitogen-activated protein kinase kinase kinase kinase 3
Target Function
May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.
Target Protein Families
Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily
Target Tissue Specificity
Ubiquitously expressed in all tissues examined, with high levels in heart, brain, placenta, skeletal muscle, kidney and pancreas and lower levels in lung and liver.
Target Synonyms
MAP4K3; RAB8IPL1Mitogen-activated protein kinase kinase kinase kinase 3; EC 2.7.11.1; Germinal center kinase-related protein kinase; GLK; MAPK/ERK kinase kinase kinase 3; MEK kinase kinase 3; MEKKK 3
Target Background
This gene encodes a member of the mitogen-activated protein kinase kinase kinase kinase family. The encoded protein activates key effectors in cell signalling, among them c-Jun. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.
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