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The antibody against MARC1 was raised in rabbit using the Synthetic peptide of Human MARC1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against MARC1 was raised in rabbit using the Synthetic peptide of Human MARC1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$299.00
| Cat.No | ADC-27151A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MARC1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Synthetic peptide of Human MARC1 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q5VT66 |
Uniprot Id
Q5VT66
Target Species
Human
Target Name
MTARC1
Target Full Name
Mitochondrial amidoxime-reducing component 1
Target Function
Catalyzes the reduction of N-oxygenated molecules, acting as a counterpart of cytochrome P450 and flavin-containing monooxygenases in metabolic cycles. As a component of prodrug-converting system, reduces a multitude of N-hydroxylated prodrugs particularly amidoximes, leading to increased drug bioavailability. May be involved in mitochondrial N(omega)-hydroxy-L-arginine (NOHA) reduction, regulating endogenous nitric oxide levels and biosynthesis. Postulated to cleave the N-OH bond of N-hydroxylated substrates in concert with electron transfer from NADH to cytochrome b5 reductase then to cytochrome b5, the ultimate electron donor that primes the active site for substrate reduction.
Target Subcellular Location
Mitochondrion outer membrane; Single-pass type II membrane protein. Membrane; Lipid-anchor. Note=Mitochondrial import is mediated by AA 1-40 and requires ATP.
Target Synonyms
MTARC1; MARC1; MOSC1Mitochondrial amidoxime-reducing component 1; mARC1; EC 1.7.-.-; Molybdenum cofactor sulfurase C-terminal domain-containing protein 1; MOSC domain-containing protein 1; Moco sulfurase C-terminal domain-containing protein 1
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