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The antibody against MAS1 was raised in rabbit using the Recombinant Human Proto-oncogene Mas protein (246-325AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against MAS1 was raised in rabbit using the Recombinant Human Proto-oncogene Mas protein (246-325AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
Immunohistochemistry of paraffin-embedded human breast cancer using MAS1 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human testis tissue using MAS1 Antibody at dilution of 1:1002
| Cat.No | ADC-40413A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MAS1 |
| Target Synonyms | MAS1; MAS; Proto-oncogene Mas | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Proto-oncogene Mas protein (246-325AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P04201 |
Uniprot Id
P04201
Target Species
Human
Target Name
MAS1
Target Full Name
Proto-oncogene Mas
Target Function
Receptor for angiotensin 1-7. Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), although it up-regulates AGTR1 receptor levels. Positive regulation of AGTR1 levels occurs through activation of the G-proteins GNA11 and GNAQ, and stimulation of the protein kinase C signaling cascade. The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1.
Target Involvement
The MAS oncogene has a weak focus-inducing activity in transfected NIH 3T3 cells.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
G-protein coupled receptor 1 family
Target Synonyms
MAS1; MAS; Proto-oncogene Mas
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