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The antibody against MATN3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 277-486 of human MATN3 (NP_002372.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against MATN3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 277-486 of human MATN3 (NP_002372.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-00767A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MATN3 |
| Target Synonyms | HOA; OS2; EDM5; DIPOA; OADIP; SEMDBCD; MATN3 | Form | Liquid |
| Species Reactivity | Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse brain, Mouse liver, Rat liver | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 277-486 of human MATN3 (NP_002372.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | O15232 | Immunogen Sequence |
Uniprot Id
O15232
Target Species
Human
Target Name
MATN3
Target Full Name
Matrilin-3
Target Function
Major component of the extracellular matrix of cartilage and may play a role in the formation of extracellular filamentous networks.
Target Involvement
Multiple epiphyseal dysplasia 5 (EDM5); Spondyloepimetaphyseal dysplasia MATN3-related (SEMD-MATN3); Osteoarthritis 2 (OS2)
Target Subcellular Location
Secreted.
Target Tissue Specificity
Expressed only in cartilaginous tissues, such as vertebrae, ribs and shoulders.
Target Research Area
Others
Target Synonyms
AV009181; DIPOA; EDM5; HOA; MATN3; MATN3_HUMAN; Matrilin 3; Matrilin-3; OADIP; OS2
Target Background
This gene encodes a member of von Willebrand factor A domain containing protein family. This family of proteins is thought to be involved in the formation of filamentous networks in the extracellular matrices of various tissues. This protein contains two von Willebrand factor A domains; it is present in the cartilage extracellular matrix and has a role in the development and homeostasis of cartilage and bone. Mutations in this gene result in multiple epiphyseal dysplasia.
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