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The antibody against MBIP was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-344 of human MBIP (NP_057670.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against MBIP was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-344 of human MBIP (NP_057670.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-07036A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MBIP |
| Target Synonyms | MBIP | Form | Liquid |
| Species Reactivity | Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat brain | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-344 of human MBIP (NP_057670.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9NS73 | Immunogen Sequence |
Uniprot Id
Q9NS73
Target Species
Human
Target Name
MBIP
Target Full Name
MAP3K12-binding inhibitory protein 1
Target Function
Inhibits the MAP3K12 activity to induce the activation of the JNK/SAPK pathway. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.
Target Subcellular Location
Nucleus. Cytoplasm. Note=Shows a cytoplasmic localization when coexpressed with MAP3K12.
Target Tissue Specificity
Ubiquitous. High expression seen in the heart and lung.
Target Synonyms
MAP3K12 binding inhibitory protein 1; MAP3K12-binding inhibitory protein 1; MAPK upstream kinase binding inhibitory protein; MAPK upstream kinase-binding inhibitory protein; Mbip; MBIP1_HUMAN; MUK binding inhibitory protein; MUK-binding inhibitory protein; OTTHUMP00000178844
Target Background
Enables identical protein binding activity and protein kinase inhibitor activity. Involved in histone H3 acetylation; positive regulation of JNK cascade; and positive regulation of gene expression. Located in cytosol; nucleolus; and nucleoplasm.
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