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The antibody against MBIP was raised in rabbit using the Human MBIP as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against MBIP was raised in rabbit using the Human MBIP as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$600.00
| Cat.No | ADC-52786A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MBIP |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Human MBIP | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9NS73 |
Uniprot Id
Q9NS73
Target Species
Human
Target Name
MBIP
Target Full Name
MAP3K12-binding inhibitory protein 1
Target Function
Inhibits the MAP3K12 activity to induce the activation of the JNK/SAPK pathway. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.
Target Subcellular Location
Nucleus. Cytoplasm. Note=Shows a cytoplasmic localization when coexpressed with MAP3K12.
Target Tissue Specificity
Ubiquitous. High expression seen in the heart and lung.
Target Synonyms
MAP3K12 binding inhibitory protein 1; MAP3K12-binding inhibitory protein 1; MAPK upstream kinase binding inhibitory protein; MAPK upstream kinase-binding inhibitory protein; Mbip; MBIP1_HUMAN; MUK binding inhibitory protein; MUK-binding inhibitory protein; OTTHUMP00000178844
Target Background
Enables identical protein binding activity and protein kinase inhibitor activity. Involved in histone H3 acetylation; positive regulation of JNK cascade; and positive regulation of gene expression. Located in cytosol; nucleolus; and nucleoplasm.
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