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The antibody against MC5R was raised in rabbit using the Recombinant Human Melanocortin receptor 5 protein (1-37AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against MC5R was raised in rabbit using the Recombinant Human Melanocortin receptor 5 protein (1-37AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
Immunohistochemistry of paraffin-embedded human glioma using MC5R Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human brain tissue using MC5R Antibody at dilution of 1:1002
| Cat.No | ADC-08900A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MC5R |
| Target Synonyms | MC5R; Melanocortin receptor 5; MC5-R; MC-2 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Melanocortin receptor 5 protein (1-37AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P33032 |
Uniprot Id
P33032
Target Species
Human
Target Name
MC5R
Target Full Name
Melanocortin receptor 5
Target Function
Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
G-protein coupled receptor 1 family
Target Tissue Specificity
Expressed in the brain but not in the melanoma cells.
Target Research Area
Neuroscience
Target Synonyms
MC5R; Melanocortin receptor 5; MC5-R; MC-2
Target Background
This gene encodes a member of the seven-pass transmembrane G protein-coupled melanocortin receptor protein family that stimulate cAMP signal transduction. The encoded protein is a receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone and is suggested to play a role in sebum generation.
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