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The antibody against MCAT was raised in rabbit using the Recombinant Human Malonyl-CoA-acyl carrier protein transacylase, mitochondrial protein (22-117AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
The antibody against MCAT was raised in rabbit using the Recombinant Human Malonyl-CoA-acyl carrier protein transacylase, mitochondrial protein (22-117AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
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Immunohistochemistry of paraffin-embedded human liver tissue using MCAT Antibody at dilution of 1:1002
| Cat.No | ADC-09049A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MCAT |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Malonyl-CoA-acyl carrier protein transacylase, mitochondrial protein (22-117AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8IVS2 |
Uniprot Id
Q8IVS2
Target Species
Human
Target Name
MCAT
Target Full Name
Malonyl-CoA-acyl carrier protein transacylase, mitochondrial
Target Function
Catalyzes the transfer of a malonyl moiety from malonyl-CoA to the free thiol group of the phosphopantetheine arm of the mitochondrial ACP protein (NDUFAB1). This suggests the existence of the biosynthesis of fatty acids in mitochondria.
Target Subcellular Location
Mitochondrion.
Target Protein Families
Type II malonyltransferase family
Target Synonyms
[Acyl-carrier-protein] malonyltransferase; FabD; FABD_HUMAN; FASN 2C; FASN2C; Malonyl CoA acyl carrier protein transacylase; Malonyl CoA acyl carrier protein transacylase mitochondrial; Malonyl CoA:ACP acyltransferase (mitochondrial); Malonyl CoA:ACP acyltransferase; Malonyl CoA:acyl carrier protein transacylase mitochondrial; Malonyl-CoA-acyl carrier protein transacylase; Mcat; MCT; MCT1; MGC47838; mitochondrial; Mitochondrial malonyl CoA:ACP acyltransferase; Mitochondrial malonyltransferase; NET62
Target Background
The protein encoded by this gene is found exclusively in the mitochondrion, where it catalyzes the transfer of a malonyl group from malonyl-CoA to the mitochondrial acyl carrier protein. The encoded protein may be part of a fatty acid synthase complex that is more like the type II prokaryotic and plastid complexes rather than the type I human cytosolic complex. Alternative splicing results in multiple transcript variants encoding different isoforms.
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