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The antibody against MDH2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 59-338 of human MDH2 (NP_005909.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against MDH2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 59-338 of human MDH2 (NP_005909.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-10305A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MDH2 |
| Target Synonyms | MDH; MOR1; DEE51; M-MDH; EIEE51; MGC:3559; MDH2 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, Mouse heart, Mouse kidney, 293T, A-549, HepG2, Jurkat, MCF7, Mouse skeletal muscle | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 59-338 of human MDH2 (NP_005909.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P40926 | Immunogen Sequence |
Uniprot Id
P40926
Target Species
Human
Target Name
MDH2
Target Full Name
Malate dehydrogenase, mitochondrial
Target Involvement
Epileptic encephalopathy, early infantile, 51 (EIEE51)
Target Subcellular Location
Mitochondrion matrix.
Target Protein Families
LDH/MDH superfamily, MDH type 1 family
Target Research Area
Signal Transduction
Target Synonyms
M MDH; Malate dehydrogenase 2; NAD (mitochondrial); Malate dehydrogenase; Malate dehydrogenase; mitochondrial; MDH; mdh2; MDHM_HUMAN; MGC:3559; mitochondrial; Mitochondrial malate dehydrogenase 2; NAD; Mor 1; MOR1
Target Background
Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. The protein encoded by this gene is localized to the mitochondria and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. Several transcript variants encoding different isoforms have been found for this gene.
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