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The antibody against ME1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human ME1 (NP_002386.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against ME1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human ME1 (NP_002386.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-11844A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ME1 |
| Target Synonyms | MES; HUMNDME; ME1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.05% proclin300, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse kidney, MCF7, Mouse liver, Mouse testis, PC-12, Rat liver | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human ME1 (NP_002386.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P48163 | Immunogen Sequence |
Uniprot Id
P48163
Target Species
Human
Target Name
ME1
Target Full Name
NADP-dependent malic enzyme
Target Subcellular Location
Cytoplasm.
Target Protein Families
Malic enzymes family
Target Tissue Specificity
Expressed in all tissues tested including liver, placenta and white adipose tissue.
Target Synonyms
Cytosolic malic enzyme 1 ; HUMNDME; Malate dehydrogenase ; Malic enzyme 1; Malic enzyme 1; NADP(+) dependent; cytosolic; Malic enzyme 1; soluble ; Malic enzyme; cytoplasmic ; MAOX_HUMAN; ME1; MES; NADP dependent malic enzyme; NADP ME; NADP-dependent malic enzyme; NADP-ME; Pyruvic malic carboxylase
Target Background
This gene encodes a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet.
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