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The antibody against MED18 was raised in rabbit using the Synthesized peptide derived from internal of Human MED18. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
The antibody against MED18 was raised in rabbit using the Synthesized peptide derived from internal of Human MED18. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
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Western blot analysis of extracts from Jurkat cells and COLO cells, using MED18 antibody.
| Cat.No | ADC-41152A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MED18 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from internal of Human MED18. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9BUE0 |
Uniprot Id
Q9BUE0
Target Species
Human
Target Name
MED18
Target Full Name
Mediator of RNA polymerase II transcription subunit 18
Target Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Target Subcellular Location
Nucleus.
Target Protein Families
Mediator complex subunit 18 family
Target Synonyms
FLJ20045; hMED 18; hMED18; Human Mediator of RNA Polymerase II Transcription; MED 18; med18; MED18_HUMAN; Mediator complex subunit 18; Mediator of RNA polymerase II transcription subunit 18; Mediator of RNA polymerase II transcription subunit 18 homolog ; OTTHUMP00000003645; p28b; TRAP/mediator complex subunit p28b
Target Background
MED18 is a component of the Mediator complex, which is a coactivator for DNA-binding factors that activate transcription via RNA polymerase II (Sato et al., 2003 [PubMed 12584197]).
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