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The antibody against MED8 was raised in rabbit using the Synthesized peptide derived from Internal of Human MED8. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
The antibody against MED8 was raised in rabbit using the Synthesized peptide derived from Internal of Human MED8. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
$297.00
Western blot analysis of extracts from Jurkat/K562 cells, using MED8 antibody.
| Cat.No | ADC-41151A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MED8 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from Internal of Human MED8. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96G25 |
Uniprot Id
Q96G25
Target Species
Human
Target Name
MED8
Target Full Name
Mediator of RNA polymerase II transcription subunit 8
Target Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May play a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins.
Target Subcellular Location
Nucleus.
Target Protein Families
Mediator complex subunit 8 family
Target Synonyms
Activator recruited cofactor 32 kDa component; Activator-recruited cofactor 32 kDa component; ARC32; med8; MED8_HUMAN; Mediator complex subunit 8; Mediator of RNA polymerase II transcription subunit 8; Mediator of RNA polymerase II transcription subunit 8 homolog
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