Rabbit anti-Human MFF Polyclonal Antibody

The antibody against MFF was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human MFF (NP_064579.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

ADA-12457A

Number

Cat.No	ADA-12457A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	MFF
Target Synonyms	EMPF2; GL004; C2orf33; MFF	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	Rat heart	Application	ELISA, WB, IHC-P

Cat.No

ADA-12457A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

MFF

Target Synonyms

EMPF2; GL004; C2orf33; MFF

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

Rat heart

Application

ELISA, WB, IHC-P

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MFF (NP_064579.3).	Target Species	Human
Immunogen Sequence	MSKGTSSDTSLGRVSRAAFPSPTAAEMAEISRIQYEMEYTEGISQRMRVPEKLKVAPPNADLEQGFQEGVPNASVIMQVPERIVVAGNNEDVSFSRPADL	Uniprot ID	Q9GZY8

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MFF (NP_064579.3).

Target Species

Human

Immunogen Sequence

MSKGTSSDTSLGRVSRAAFPSPTAAEMAEISRIQYEMEYTEGISQRMRVPEKLKVAPPNADLEQGFQEGVPNASVIMQVPERIVVAGNNEDVSFSRPADL

Uniprot ID

Q9GZY8

Background Information

Uniprot Id

Q9GZY8
Target Species

Human
Target Name

MFF
Target Full Name

Mitochondrial fission factor
Target Function

Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface. May be involved in regulation of synaptic vesicle membrane dynamics by recruitment of DNM1L to clathrin-containing vesicles.
Target Involvement

Encephalopathy due to defective mitochondrial and peroxisomal fission 2 (EMPF2)
Target Subcellular Location

Mitochondrion outer membrane; Single-pass type IV membrane protein. Peroxisome. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle.
Target Protein Families

Tango11 family
Target Tissue Specificity

Highly expressed in heart, kidney, liver, brain, muscle, and stomach.
Target Research Area

Others
Target Synonyms

C2orf33 ; Chromosome 2 open reading frame 33; DKFZp666J168; GL004 ; Mff; MFF_HUMAN; MGC110913; Mitochondrial fission factor; OTTHUMP00000164235
Target Background

This is a nuclear gene encoding a protein that functions in mitochondrial and peroxisomal fission. The encoded protein recruits dynamin-1-like protein (DNM1L) to mitochondria. There are multiple pseudogenes for this gene on chromosomes 1, 5, and X. Alternative splicing results in multiple transcript variants.

Rabbit anti-Human MFF Polyclonal Antibody

Specifications

Immunogen Information

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