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The antibody against MLC1 was raised in rabbit using the Recombinant Human Membrane protein MLC1 protein (1-49AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against MLC1 was raised in rabbit using the Recombinant Human Membrane protein MLC1 protein (1-49AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
Immunohistochemistry of paraffin-embedded human brain tissue using MLC1 Antibody at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using MLC1 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)2
| Cat.No | ADC-14364A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MLC1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Membrane protein MLC1 protein (1-49AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q15049 |
Uniprot Id
Q15049
Target Species
Human
Target Name
MLC1
Target Full Name
Membrane protein MLC1
Target Function
Regulates the response of astrocytes to hypo-osmosis by promoting calcium influx.
Target Involvement
Leukoencephalopathy, megalencephalic, with subcortical cysts, 1 (MLC1)
Target Subcellular Location
Membrane; Multi-pass membrane protein. Cell membrane. Cytoplasm, perinuclear region. Endoplasmic reticulum.
Target Tissue Specificity
Expressed in the brain, with highest levels found in the amygdala, nucleus caudatus, thalamus and hippocampus.
Target Synonyms
KIAA0027; LVM; Megalencephalic leukoencephalopathy with subcortical cysts 1; Membrane protein MLC1; MLC; MLC1; MLC1_HUMAN; VL; WKL1
Target Background
The function of this gene product is unknown; however, homology to other proteins suggests that it may be an integral membrane transporter. Mutations in this gene have been associated with megalencephalic leukoencephalopathy with subcortical cysts, an autosomal recessive neurological disorder. Alternatively spliced transcript variants encoding different isoforms have been identified.
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