Rabbit anti-Human MLD Monoclonal Antibody

The antibody against MLD was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human MLD (NP_003667.1) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-14568A

Number

Cat.No	ADA-14568A	Clonality	Monoclonal
Host Species	Rabbit	Target Name	MLD
Target Synonyms	MLD; DEGS; DES1; Des-1; FADS7; HLD18; MIG15; DEGS-1	Form	Liquid
Species Reactivity	Human	Isotype	IgG
Storage Buffer	50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	U-87 MG	Application	ELISA, WB

Cat.No

ADA-14568A

Clonality

Monoclonal

Host Species

Rabbit

Target Name

MLD

Target Synonyms

MLD; DEGS; DES1; Des-1; FADS7; HLD18; MIG15; DEGS-1

Form

Liquid

Species Reactivity

Human

Isotype

IgG

Storage Buffer

50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

U-87 MG

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human MLD (NP_003667.1).	Target Species	Human
Immunogen Sequence	MGSRVSREDFEWVYTDQPHADRRREILAKYPEIKSLMKPDPNLIWIIIMMVLTQLGAFYIVKDLDWKWVIFGAYAFGSCINHSMTLAIHEIAHNAAFGNC	Uniprot ID	O15121

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human MLD (NP_003667.1).

Target Species

Human

Immunogen Sequence

MGSRVSREDFEWVYTDQPHADRRREILAKYPEIKSLMKPDPNLIWIIIMMVLTQLGAFYIVKDLDWKWVIFGAYAFGSCINHSMTLAIHEIAHNAAFGNC

Uniprot ID

O15121

Background Information

Uniprot Id

O15121
Target Species

Human
Target Name

DEGS1
Target Full Name

Sphingolipid delta(4)-desaturase DES1
Target Function

Has sphingolipid-delta-4-desaturase activity. Converts D-erythro-sphinganine to D-erythro-sphingosine (E-sphing-4-enine). Catalyzes the equilibrium isomerization of retinols.
Target Subcellular Location

Mitochondrion membrane. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Target Protein Families

Fatty acid desaturase type 1 family, DEGS subfamily
Target Tissue Specificity

Ubiquitous.
Target Synonyms

DEGS1; DES1; MLD; MIG15; Sphingolipid delta(4-desaturase DES1; Cell migration-inducing gene 15 protein; Degenerative spermatocyte homolog 1; Dihydroceramide desaturase-1; Membrane lipid desaturase
Target Background

This gene encodes a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor.

Rabbit anti-Human MLD Monoclonal Antibody

Specifications

Immunogen Information

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