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The antibody against MLXIP was raised in rabbit using the Recombinant Human MLX-interacting protein (1-217AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against MLXIP was raised in rabbit using the Recombinant Human MLX-interacting protein (1-217AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using MLXIP Antibody at dilution of 1:100
| Cat.No | ADC-44275A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MLXIP |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human MLX-interacting protein (1-217AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9HAP2 |
Uniprot Id
Q9HAP2
Target Species
Human
Target Name
MLXIP
Target Full Name
MLX-interacting protein
Target Function
Binds DNA as a heterodimer with MLX and activates transcription. Binds to the canonical E box sequence 5'-CACGTG-3'. Plays a role in transcriptional activation of glycolytic target genes. Involved in glucose-responsive gene regulation.
Target Subcellular Location
Cytoplasm. Nucleus. Mitochondrion outer membrane.
Target Tissue Specificity
Widely expressed in adult tissues. Most abundant in skeletal muscle.
Target Research Area
Transcription
Target Synonyms
MLXIP; BHLHE36; KIAA0867; MIR; MONDOA; MLX-interacting protein; Class E basic helix-loop-helix protein 36; bHLHe36; Transcriptional activator MondoA
Target Background
This gene encodes a protein that functions as part of a heterodimer to activate transcription. The encoded protein forms a heterodimer with Max-like protein X (MLX) and is involved in the regulation of genes in response to cellular glucose levels.
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