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The antibody against MMEL1 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 350-450 of human MMEL1 (NP_258428.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against MMEL1 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 350-450 of human MMEL1 (NP_258428.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-05229A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MMEL1 |
| Target Synonyms | NL1; NL2; SEP; NEP2; MMEL2; NEPII; MMEL1 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | 293T, OVCAR3 | Application | ELISA, WB |
| Immunogen Description | A synthetic peptide corresponding to a sequence within amino acids 350-450 of human MMEL1 (NP_258428.2). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | NWTLFIQTVLSSVKIKLLPDEEVVVYGIPYLQNLENIIDTYSARTIQNYLVWRLVLDRIGSLSQRFKDTRVNYRKALFGTMVEEVRWRECVGYVNSNMENA | Uniprot ID | Q495T6 |
Uniprot Id
Q495T6
Target Species
Human
Target Name
MMEL1
Target Full Name
Membrane metallo-endopeptidase-like 1
Target Function
Metalloprotease involved in sperm function, possibly by modulating the processes of fertilization and early embryonic development. Degrades a broad variety of small peptides with a preference for peptides shorter than 3 kDa containing neutral bulky aliphatic or aromatic amino acid residues. Shares the same substrate specificity with MME and cleaves peptides at the same amide bond.
Target Subcellular Location
Membrane; Single-pass type II membrane protein. Secreted.
Target Protein Families
Peptidase M13 family
Target Tissue Specificity
Predominantly expressed in testis. Weakly expressed in brain, kidney and heart.
Target Synonyms
Mel transforming oncogene like 1; Membrane metallo endopeptidase like 1 ; Membrane metallo endopeptidase like 2; Membrane metallo-endopeptidase-like 1; Membrane metallo-endopeptidase-like 2; MMEL1; MMEL1_HUMAN; NEP2; NEP2(m); NEP2(s); NEPII; Neprilysin 2; Neprilysin II; Neprilysin Like 1; Neprilysin-2; Neprilysin-2 secreted; Neprilysin-like Protease beta; Neprilysin-like Protease gamma; NL1; NL2; SEP; soluble form; Soluble secreted endopeptidase
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