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Rabbit anti-Human MMP10 Polyclonal Antibody

The antibody against MMP10 was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human MMP-10. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on IHC, IF, ELISA.

ADC-35011A

The antibody against MMP10 was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human MMP-10. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on IHC, IF, ELISA.

$167.00

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Specifications


Cat.No ADC-35011A ClonalityPolyclonal
Host SpeciesRabbitTarget NameMMP10
FormLiquidSpecies ReactivityHuman, Mouse, Rat
IsotypeIgGStorage Buffer0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol
Purification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.ConjugateNon-conjugated
ApplicationELISA, IF, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from the C-terminal region of Human MMP-10.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP09238
Background Information
  • Uniprot Id

    P09238

  • Target Species

    Human

  • Target Name

    MMP10

  • Target Full Name

    Stromelysin-2

  • Target Function

    Can degrade fibronectin, gelatins of type I, III, IV, and V; weakly collagens III, IV, and V. Activates procollagenase.

  • Target Subcellular Location

    Secreted, extracellular space, extracellular matrix.

  • Target Protein Families

    Peptidase M10A family

  • Target Research Area

    Developmental Biology

  • Target Synonyms

    Matrix metallopeptidase 10 (stromelysin 2); Matrix metalloprotease 10; Matrix metalloproteinase 10 (stromelysin 2); Matrix metalloproteinase 10; Matrix metalloproteinase-10; MMP 10; MMP-10; Mmp10; MMP10_HUMAN; SL 2; SL-2; SL2; STMY 2; STMY2; Stromelysin 2; Stromelysin II; Stromelysin-2; Stromelysin2; StromelysinII; Transin 2; Transin-2; Transin2

  • Target Background

    This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down fibronectin, laminin, elastin, proteoglycan core protein, gelatins, and several types of collagen. The gene is part of a cluster of MMP genes on chromosome 11.

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