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The antibody against MON1A was raised in Rabbit using the recombinant protein of human MON1A as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against MON1A was raised in Rabbit using the recombinant protein of human MON1A as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-10534A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MON1A |
| Target Synonyms | SAND1; MON1A | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | K-562 | Application | ELISA, WB |
| Immunogen Description | Recombinant protein of human MON1A. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q86VX9 |
Uniprot Id
Q86VX9
Target Species
Human
Target Name
MON1A
Target Full Name
Vacuolar fusion protein MON1 homolog A
Target Function
Plays an important role in membrane trafficking through the secretory apparatus. Not involved in endocytic trafficking to lysosomes. Acts in concert with CCZ1, as a guanine exchange factor (GEF) for RAB7, promotes the exchange of GDP to GTP, converting it from an inactive GDP-bound form into an active GTP-bound form.
Target Protein Families
MON1/SAND family
Target Research Area
Signal Transduction
Target Synonyms
FLJ97088; MGC13272; MON1 homolog A; MON1A; MON1A_HUMAN; SAND1; Vacuolar fusion protein MON1 homolog A
Target Background
Enables guanyl-nucleotide exchange factor activity. Predicted to be involved in protein secretion. Predicted to act upstream of or within cellular iron ion homeostasis and protein transport. Part of Mon1-Ccz1 complex.
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