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The antibody against MOV10L1 was raised in rabbit using the Recombinant Human RNA helicase Mov10l1 protein (336-425AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against MOV10L1 was raised in rabbit using the Recombinant Human RNA helicase Mov10l1 protein (336-425AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
$299.00
| Cat.No | ADC-04625A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MOV10L1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human RNA helicase Mov10l1 protein (336-425AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9BXT6 |
Uniprot Id
Q9BXT6
Target Species
Human
Target Name
MOV10L1
Target Full Name
RNA helicase Mov10l1
Target Function
ATP-dependent RNA helicase required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the primary piRNA metabolic process. Specifically binds to piRNA precursors and promotes the generation of intermediate piRNA processing fragments that are subsequently loaded to Piwi proteins. Acts via its ATP-dependent RNA helicase activity: displays 5'-3' RNA unwinding activity and probably mediates unwinding and funneling of single-stranded piRNA precursor transcripts to the endonuclease that catalyzes the first cleavage step of piRNA processing to generate piRNA intermediate fragments that are subsequently loaded to Piwi proteins.
Target Subcellular Location
Cytoplasm.
Target Protein Families
DNA2/NAM7 helicase family, SDE3 subfamily
Target Tissue Specificity
[Isoform 1]: Specifically expressed in testis.
Target Synonyms
Cardiac helicase activated by MEF2 protein; Cardiac specific RNA helicase; CHAMP; Csm; M10L1_HUMAN; Moloney leukemia virus 10 like protein 1; Moloney leukemia virus 10-like protein 1; MOV10 like 1; MOV10 like protein 1; MOV10-like protein 1; MOV10L1; Mov10l1; Moloney leukemia virus 10 like 1; homolog (mouse); Putative helicase Mov10l1
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