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The antibody against MPC1 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 50-109 of human MPC1 (NP_057182.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IP, ELISA.
The antibody against MPC1 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 50-109 of human MPC1 (NP_057182.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IP, ELISA.
| Cat.No | ADA-07376A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MPC1 |
| Target Synonyms | MPYCD; BRP44L; CGI-129; SLC54A1; MPC1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat heart, HepG2, K-562, Mouse liver | Application | ELISA, WB, IP |
| Immunogen Description | A synthetic peptide corresponding to a sequence within amino acids 50-109 of human MPC1 (NP_057182.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | IISGRMTFALCCYSLTFMRFAYKVQPRNWLLFACHATNEVAQLIQGGRLIKHEMTKTASA | Uniprot ID | Q9Y5U8 |
Uniprot Id
Q9Y5U8
Target Species
Human
Target Name
MPC1
Target Full Name
Mitochondrial pyruvate carrier 1
Target Function
Mediates the uptake of pyruvate into mitochondria.
Target Involvement
Mitochondrial pyruvate carrier deficiency (MPYCD)
Target Subcellular Location
Mitochondrion inner membrane; Multi-pass membrane protein.
Target Protein Families
Mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family
Target Synonyms
MPYCD; BRP44L; CGI-129; SLC54A1; MPC1
Target Background
The protein encoded by this gene is part of an MPC1/MPC2 heterodimer that is responsible for transporting pyruvate into mitochondria. The encoded protein is found in the inner mitochondrial membrane. Defects in this gene are a cause of mitochondrial pyruvate carrier deficiency. Several transcript variants, some protein coding and one non-protein coding, have been found for this gene.
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