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Rabbit anti-Human MRAP Polyclonal Antibody

The antibody against MRAP was raised in rabbit using the Recombinant Human Melanocortin-2 receptor accessory protein (59-172AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.

ADC-04686A

The antibody against MRAP was raised in rabbit using the Recombinant Human Melanocortin-2 receptor accessory protein (59-172AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.

$299.00

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Specifications


Cat.No ADC-04686A ClonalityPolyclonal
Host SpeciesRabbitTarget NameMRAP
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISA, IFStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Melanocortin-2 receptor accessory protein (59-172AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ8TCY5
Background Information
  • Uniprot Id

    Q8TCY5

  • Target Species

    Human

  • Target Name

    MRAP

  • Target Full Name

    Melanocortin-2 receptor accessory protein

  • Target Function

    Modulator of melanocortin receptors (MC1R, MC2R, MC3R, MC4R and MC5R). Acts by increasing ligand-sensitivity of melanocortin receptors and enhancing generation of cAMP by the receptors. Required both for MC2R trafficking to the cell surface of adrenal cells and for signaling in response to corticotropin (ACTH). May be involved in the intracellular trafficking pathways in adipocyte cells.

  • Target Involvement

    Glucocorticoid deficiency 2 (GCCD2)

  • Target Subcellular Location

    Cell membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.

  • Target Protein Families

    MRAP family

  • Target Tissue Specificity

    Expressed in adrenal cortex, testis, breast, thyroid, lymph node, ovary and fat. Expressed in adipose tissues.

  • Target Synonyms

    B27; C21orf61; FALP; Fat cell-specific low molecular weight protein; Fat tissue-specific low MW protein; FGD2; GCCD2; Melanocortin-2 receptor accessory protein; Mrap; MRAP_HUMAN

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