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Rabbit anti-Human MRM2 Polyclonal Antibody, Biotin conjugated

The antibody against MRM2 was raised in rabbit using the Recombinant Human rRNA methyltransferase 2, mitochondrial protein (19-246AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

ADC-17983A

The antibody against MRM2 was raised in rabbit using the Recombinant Human rRNA methyltransferase 2, mitochondrial protein (19-246AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

$299.00

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Specifications


Cat.No ADC-17983A ClonalityPolyclonal
Host SpeciesRabbitTarget NameMRM2
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateBiotin conjugated
ApplicationELISAStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human rRNA methyltransferase 2, mitochondrial protein (19-246AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9UI43
Background Information
  • Uniprot Id

    Q9UI43

  • Target Species

    Human

  • Target Name

    MRM2

  • Target Full Name

    rRNA methyltransferase 2, mitochondrial

  • Target Function

    S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methyluridine at position 1369 (Um1369) in the 16S mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a universally conserved modification in the peptidyl transferase domain of the mtLSU rRNA.

  • Target Subcellular Location

    Mitochondrion.

  • Target Protein Families

    Class I-like SAM-binding methyltransferase superfamily, RNA methyltransferase RlmE family

  • Target Tissue Specificity

    Widely expressed, with highest expression in muscle, placenta, and heart.

  • Target Synonyms

    FJH1; FTSJ2; MRM2; Protein ftsJ homolog 2; Putative ribosomal RNA methyltransferase 2; Ribosomal RNA methyltransferase 2; RRMJ2_HUMAN; rRNA (uridine-2''-O-)-methyltransferase

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