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The antibody against MRPL21 was raised in rabbit using the Recombinant Human 39S ribosomal protein L21, mitochondrial protein (40-205AA) as the immunogen. This antibody exists as a hrp conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against MRPL21 was raised in rabbit using the Recombinant Human 39S ribosomal protein L21, mitochondrial protein (40-205AA) as the immunogen. This antibody exists as a hrp conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-19424A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MRPL21 |
| Target Synonyms | MRPL21 antibody; 39S ribosomal protein L21 antibody; mitochondrial antibody; L21mt antibody; MRP-L21 antibody; Mitochondrial large ribosomal subunit protein bL21m antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | HRP conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human 39S ribosomal protein L21, mitochondrial protein (40-205AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q7Z2W9 |
Uniprot Id
Q7Z2W9
Target Species
Human
Target Name
MRPL21
Target Full Name
Large ribosomal subunit protein bL21m
Target Subcellular Location
Mitochondrion.
Target Protein Families
Bacterial ribosomal protein bL21 family
Target Synonyms
MRPL21; 39S ribosomal protein L21; mitochondrial; L21mt; MRP-L21; Mitochondrial large ribosomal subunit protein bL21m
Target Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Multiple transcript variants encoding different isoforms were identified through sequence analysis although some may be subject to nonsense-mediated decay (NMD).
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