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The antibody against MRPL24 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-216 of human MRPL24 (NP_078816.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against MRPL24 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-216 of human MRPL24 (NP_078816.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-09726A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MRPL24 |
| Target Synonyms | L24mt; MRP-L18; MRP-L24; MRPL24 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse heart, Jurkat, MCF7, Rat kidney, Rat liver, Rat testis, SKOV3 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-216 of human MRPL24 (NP_078816.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q96A35 | Immunogen Sequence |
Uniprot Id
Q96A35
Target Species
Human
Target Name
MRPL24
Target Full Name
Large ribosomal subunit protein uL24m
Target Subcellular Location
Mitochondrion.
Target Protein Families
Universal ribosomal protein uL24 family
Target Synonyms
MRPL24; 39S ribosomal protein L24; mitochondrial; L24mt; MRP-L24; Mitochondrial large ribosomal subunit protein uL24m
Target Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which is more than twice the size of its E.coli counterpart (EcoL24). Sequence analysis identified two transcript variants that encode the same protein.
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