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The antibody against MRPL38 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 35-380 of human MRPL38 (NP_115867.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against MRPL38 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 35-380 of human MRPL38 (NP_115867.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-03742A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MRPL38 |
| Target Synonyms | L38MT; RPML3; MRP-L3; HSPC262; MRP-L38; MRPL38 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse kidney, Rat brain, 293T, K-562, MCF7, Mouse brain, Mouse liver, Rat liver | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 35-380 of human MRPL38 (NP_115867.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q96DV4 | Immunogen Sequence |
Uniprot Id
Q96DV4
Target Species
Human
Target Name
MRPL38
Target Full Name
Large ribosomal subunit protein mL38
Target Subcellular Location
Mitochondrion.
Target Protein Families
Phosphatidylethanolamine-binding protein family, Mitochondrion-specific ribosomal protein mL38 subfamily
Target Synonyms
MRPL38; HSPC262; 39S ribosomal protein L38; mitochondrial; L38mt; MRP-L38; Mitochondrial large ribosomal subunit protein mL38
Target Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein.
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