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The antibody against MRPL44 was raised in rabbit using the Recombinant Human 39S ribosomal protein L44, mitochondrial protein (31-332AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against MRPL44 was raised in rabbit using the Recombinant Human 39S ribosomal protein L44, mitochondrial protein (31-332AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-24384A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MRPL44 |
| Target Synonyms | MRPL44 antibody; 39S ribosomal protein L44 antibody; mitochondrial antibody; L44mt antibody; MRP-L44 antibody; EC 3.1.26.- antibody; Mitochondrial large ribosomal subunit protein mL44 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Biotin conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human 39S ribosomal protein L44, mitochondrial protein (31-332AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9H9J2 |
Uniprot Id
Q9H9J2
Target Species
Human
Target Name
MRPL44
Target Full Name
Large ribosomal subunit protein mL44
Target Function
Component of the 39S subunit of mitochondrial ribosome. May have a function in the assembly/stability of nascent mitochondrial polypeptides exiting the ribosome.
Target Involvement
Combined oxidative phosphorylation deficiency 16 (COXPD16)
Target Subcellular Location
Mitochondrion.
Target Protein Families
Ribonuclease III family, Mitochondrion-specific ribosomal protein mL44 subfamily
Target Synonyms
MRPL44; 39S ribosomal protein L44; mitochondrial; L44mt; MRP-L44; EC 3.1.26.-; Mitochondrial large ribosomal subunit protein mL44
Target Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein.
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