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Rabbit anti-Human MRPL50 Polyclonal Antibody

The antibody against MRPL50 was raised in rabbit using the Synthesized peptide derived from internal of Human MRPL50. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.

ADC-41128A

The antibody against MRPL50 was raised in rabbit using the Synthesized peptide derived from internal of Human MRPL50. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.

$297.00

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Specifications


Cat.No ADC-41128A ClonalityPolyclonal
Host SpeciesRabbitTarget NameMRPL50
Target SynonymsMRPL50 antibody; 39S ribosomal protein L50 antibody; mitochondrial antibody; L50mt antibody; MRP-L50 antibody; Mitochondrial large ribosomal subunit protein mL50 antibodyFormLiquid
Species ReactivityHumanStorage BufferPH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+)
Purification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.ApplicationELISA, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from internal of Human MRPL50.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ8N5N7
Background Information
  • Uniprot Id

    Q8N5N7

  • Target Species

    Human

  • Target Name

    MRPL50

  • Target Full Name

    Large ribosomal subunit protein mL50

  • Target Subcellular Location

    Mitochondrion.

  • Target Protein Families

    Mitochondrion-specific ribosomal protein mL50 family

  • Target Synonyms

    MRPL50; 39S ribosomal protein L50; mitochondrial; L50mt; MRP-L50; Mitochondrial large ribosomal subunit protein mL50

  • Target Background

    Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a putative 39S subunit protein and belongs to the L47P ribosomal protein family. Pseudogenes corresponding to this gene are found on chromosomes 2p, 2q, 5p, and 10q.

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