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Rabbit anti-Human MRPL51 Polyclonal Antibody

The antibody against MRPL51 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human MRP-L51. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.

ADC-34774A

The antibody against MRPL51 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human MRP-L51. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.

$167.00

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Specifications


Cat.No ADC-34774A ClonalityPolyclonal
Host SpeciesRabbitTarget NameMRPL51
FormLiquidSpecies ReactivityHuman, Mouse
IsotypeIgGStorage Buffer0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol
Purification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.ConjugateNon-conjugated
ApplicationELISA, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from the Internal region of Human MRP-L51.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ4U2R6
Background Information
  • Uniprot Id

    Q4U2R6

  • Target Species

    Human

  • Target Name

    MRPL51

  • Target Full Name

    Large ribosomal subunit protein mL51

  • Target Subcellular Location

    Mitochondrion.

  • Target Protein Families

    Mitochondrion-specific ribosomal protein mL51 family

  • Target Synonyms

    39S ribosomal protein L51; 39S ribosomal protein L51 mitochondrial; bMRP-64; bMRP64; CDA09; HSPC241; L51mt; mitochondrial; mitochondrial ribosomal protein 64; mitochondrial ribosomal protein bMRP64; mitochondrial ribosomal protein L51 ; MRP-L51; MRP64; mrpl51; RM51_HUMAN

  • Target Background

    Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Pseudogenes corresponding to this gene are found on chromosomes 4p and 21q.

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