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The antibody against MRPL53 was raised in rabbit using the Recombinant Human 39S ribosomal protein L53, mitochondrial protein (8-113AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against MRPL53 was raised in rabbit using the Recombinant Human 39S ribosomal protein L53, mitochondrial protein (8-113AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
$299.00
Immunohistochemistry of paraffin-embedded human skin tissue using MRPL53 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human adrenal gland tissue using MRPL53 Antibody at dilution of 1:1002
| Cat.No | ADC-24374A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MRPL53 |
| Target Synonyms | MRPL53 antibody; 39S ribosomal protein L53 antibody; mitochondrial antibody; L53mt antibody; MRP-L53 antibody; Mitochondrial large ribosomal subunit protein mL53 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human 39S ribosomal protein L53, mitochondrial protein (8-113AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96EL3 |
Uniprot Id
Q96EL3
Target Species
Human
Target Name
MRPL53
Target Full Name
Large ribosomal subunit protein mL53
Target Subcellular Location
Mitochondrion.
Target Protein Families
Mitochondrion-specific ribosomal protein mL53 family
Target Synonyms
MRPL53; 39S ribosomal protein L53; mitochondrial; L53mt; MRP-L53; Mitochondrial large ribosomal subunit protein mL53
Target Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 1p.
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