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The antibody against MRPS2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-296 of human MRPS2 (NP_057118.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against MRPS2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-296 of human MRPS2 (NP_057118.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-05754A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MRPS2 |
| Target Synonyms | S2mt; CGI-91; MRP-S2; COXPD36; MRPS2 | Form | Liquid |
| Species Reactivity | Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse heart, Mouse kidney, Mouse brain, Mouse liver | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-296 of human MRPS2 (NP_057118.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9Y399 | Immunogen Sequence |
Uniprot Id
Q9Y399
Target Species
Human
Target Name
MRPS2
Target Full Name
Small ribosomal subunit protein uS2m
Target Function
Required for mitoribosome formation and stability, and mitochondrial translation.
Target Subcellular Location
Mitochondrion.
Target Protein Families
Universal ribosomal protein uS2 family
Target Synonyms
28S ribosomal protein S2; 28S ribosomal protein S2 mitochondrial; CGI 91; CGI91; Mitochondrial 28S ribosomal protein S2; mitochondrial; Mitochondrial ribosomal protein S2; MRP S2; MRP-S2; MRPS2; OTTHUMP00000022545; OTTHUMP00000022546; RT02_HUMAN; S2mt
Target Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S2 family. Alternatively spliced transcript variants have been observed for this gene.
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