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The antibody against MSI2 was raised in rabbit using the Recombinant Human RNA-binding protein Musashi homolog 2 protein (1-80AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against MSI2 was raised in rabbit using the Recombinant Human RNA-binding protein Musashi homolog 2 protein (1-80AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$299.00
| Cat.No | ADC-40091A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MSI2 |
| Target Synonyms | 2 antibody; Musashi-2 antibody; RNA binding protein Musashi homolog 2 antibody; RNA-binding protein Musashi homolog 2 antibody; WD 40 repeat protein MSI2 antibody, Drosophila, FLJ36569 antibody; MGC3245 antibody; Msi2 antibody; MSI2/HOXA9 fusion gene, homolog of, included antibody; MSI2H antibody; MSI2H_HUMAN antibody; Musashi 2 antibody; Musashi homolog 2 antibody; Musashi RNA binding protein 2 antibody; Musashi | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human RNA-binding protein Musashi homolog 2 protein (1-80AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96DH6 |
Uniprot Id
Q96DH6
Target Species
Human
Target Name
MSI2
Target Full Name
RNA-binding protein Musashi homolog 2
Target Function
RNA binding protein that regulates the expression of target mRNAs at the translation level. May play a role in the proliferation and maintenance of stem cells in the central nervous system.
Target Involvement
Chromosomal aberrations involving MSI2 may contribute to disease progression in chronic myeloid leukemia. Translocation t(7;17)(p15;q23) with HOXA9; translocation t(7;17)(q32-34;q23).
Target Subcellular Location
Cytoplasm.
Target Protein Families
Musashi family
Target Tissue Specificity
Ubiquitous; detected at low levels.
Target Synonyms
FLJ36569; MGC3245; Msi2; MSI2/HOXA9 fusion gene, included; MSI2H; MSI2H_HUMAN; Musashi 2; Musashi homolog 2; Musashi RNA binding protein 2; Musashi, Drosophila, homolog of, 2; Musashi-2; RNA binding protein Musashi homolog 2; RNA-binding protein Musashi homolog 2; WD 40 repeat protein MSI2
Target Background
This gene encodes an RNA-binding protein that is a member of the Musashi protein family. The encoded protein is transcriptional regulator that targets genes involved in development and cell cycle regulation. Mutations in this gene are associated with poor prognosis in certain types of cancers. This gene has also been shown to be rearranged in certain cancer cells.
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