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The antibody against MTHFR was raised in rabbit using the Synthesized peptide derived from the Internal region of Human MTHFR. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
The antibody against MTHFR was raised in rabbit using the Synthesized peptide derived from the Internal region of Human MTHFR. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
$167.00
Western Blot analysis of COLO205 cells using MTHFR Polyclonal Antibody
| Cat.No | ADC-38171A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MTHFR |
| Form | Liquid | Species Reactivity | Human, Mouse, Monkey |
| Isotype | IgG | Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human MTHFR. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P42898 |
Uniprot Id
P42898
Target Species
Human
Target Name
MTHFR
Target Full Name
Methylenetetrahydrofolate reductase (NADPH)
Target Function
Catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine.
Target Involvement
Methylenetetrahydrofolate reductase deficiency (MTHFRD); Ischemic stroke (ISCHSTR); Neural tube defects, folate-sensitive (NTDFS); Schizophrenia (SCZD)
Target Protein Families
Methylenetetrahydrofolate reductase family
Target Research Area
Metabolism
Target Synonyms
5 10 methylenetetrahydrofolate reductase (NADPH); 5 10 methylenetetrahydrofolate reductase; Methylenetetrahydrofolate reductase (NAD(P)H); Methylenetetrahydrofolate reductase; Methylenetetrahydrofolate reductase intermediate form; MTHFR; MTHR_HUMAN
Target Background
The protein encoded by this gene catalyzes the conversion of 5, 10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.
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