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The antibody against MTIF3 was raised in rabbit using the Recombinant Human Translation initiation factor IF-3, mitochondrial protein (1-278AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against MTIF3 was raised in rabbit using the Recombinant Human Translation initiation factor IF-3, mitochondrial protein (1-278AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human prostate cancer using MTIF3 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human lung cancer using MTIF3 Antibody at dilution of 1:1002
| Cat.No | ADC-16644A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MTIF3 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Translation initiation factor IF-3, mitochondrial protein (1-278AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9H2K0 |
Uniprot Id
Q9H2K0
Target Species
Human
Target Name
MTIF3
Target Full Name
Translation initiation factor IF-3, mitochondrial
Target Function
IF-3 binds to the 28S ribosomal subunit and shifts the equilibrum between 55S ribosomes and their 39S and 28S subunits in favor of the free subunits, thus enhancing the availability of 28S subunits on which protein synthesis initiation begins.
Target Subcellular Location
Mitochondrion.
Target Protein Families
IF-3 family
Target Research Area
Neuroscience
Target Synonyms
DC38; IF 3 ; IF 3Mt; IF-3(Mt); IF-3Mt; IF3 ; IF3(mt); IF3M_HUMAN; IF3mt; mitochondrial; Mt; MTIF3; Translation initiation factor IF 3; mitochondrial precursor; Translation initiation factor IF-3
Target Background
This gene encodes a translation initiation factor that is involved in mitochondrial protein synthesis. Polymorphism in this gene is associated with the onset of Parkinson's disease. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 5.
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