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Rabbit anti-Human MTMR12 Polyclonal Antibody

The antibody against MTMR12 was raised in rabbit using the Recombinant Human Myotubularin-related protein 12 protein (188-318AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.

ADC-04589A

The antibody against MTMR12 was raised in rabbit using the Recombinant Human Myotubularin-related protein 12 protein (188-318AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.

$299.00

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Specifications


Cat.No ADC-04589A ClonalityPolyclonal
Host SpeciesRabbitTarget NameMTMR12
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISA, IFStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Myotubularin-related protein 12 protein (188-318AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9C0I1
Background Information
  • Uniprot Id

    Q9C0I1

  • Target Species

    Human

  • Target Name

    MTMR12

  • Target Full Name

    Myotubularin-related protein 12

  • Target Function

    Acts as an adapter for the myotubularin-related phosphatases. Regulates phosphatase MTM1 protein stability and possibly its intracellular location. By stabilizing MTM1 protein levels, required for skeletal muscle maintenance but not for myogenesis.

  • Target Subcellular Location

    Cytoplasm. Sarcoplasmic reticulum. Cytoplasm, myofibril, sarcomere.

  • Target Protein Families

    Protein-tyrosine phosphatase family, Non-receptor class myotubularin subfamily

  • Target Tissue Specificity

    Expressed in skeletal muscles (at protein level). Ubiquitous with prominent expression in brain, heart, kidney, placenta, and lung.

  • Target Synonyms

    MTMR12; KIAA1682; PIP3AP; Myotubularin-related protein 12; Inactive phosphatidylinositol 3-phosphatase 12; Phosphatidylinositol 3 phosphate 3-phosphatase adapter subunit; 3-PAP; 3-phosphatase adapter protein

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