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The antibody against MTO1 was raised in rabbit using the Human MTO1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against MTO1 was raised in rabbit using the Human MTO1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$600.00
| Cat.No | ADC-47907A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MTO1 |
| Target Synonyms | MTO1 antibody; CGI-02 antibody; Protein MTO1 homolog antibody; mitochondrial antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Human MTO1 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9Y2Z2 |
Uniprot Id
Q9Y2Z2
Target Species
Human
Target Name
MTO1
Target Full Name
Protein MTO1 homolog, mitochondrial
Target Function
Involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs.
Target Involvement
Combined oxidative phosphorylation deficiency 10 (COXPD10)
Target Subcellular Location
Mitochondrion.
Target Protein Families
MnmG family
Target Tissue Specificity
Ubiquitously expressed in various tissues, but with a markedly elevated expression in tissues of high metabolic rates including cochlea.
Target Synonyms
CGI-02; COXPD10; MTO1
Target Background
This gene encodes a mitochondrial protein thought to be involved in mitochondrial tRNA modification. The encoded protein may also play a role in the expression of the non-syndromic and aminoglycoside-induced deafness phenotypes associated with a specific mutation in the mitochondrial 12S rRNA gene. Multiple transcript variants encoding different isoforms have been found for this gene.
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