Rabbit anti-Human MVD Polyclonal Antibody

The antibody against MVD was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human MVD (NP_002452.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-05192A

Number

Cat.No	ADA-05192A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	MVD
Target Synonyms	MPD; MDDase; POROK7; FP17780; MVD	Form	Liquid
Species Reactivity	Human	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	A-549, BxPC-3, LO2, U-87MG	Application	ELISA, WB

Cat.No

ADA-05192A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

MVD

Target Synonyms

MPD; MDDase; POROK7; FP17780; MVD

Form

Liquid

Species Reactivity

Human

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

A-549, BxPC-3, LO2, U-87MG

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human MVD (NP_002452.1).	Target Species	Human
Uniprot ID	P53602	Immunogen Sequence

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human MVD (NP_002452.1).

Target Species

Human

Uniprot ID

P53602

Immunogen Sequence

Background Information

Uniprot Id

P53602
Target Species

Human
Target Name

MVD
Target Full Name

Diphosphomevalonate decarboxylase
Target Function

Catalyzes the ATP dependent decarboxylation of (R)-5-diphosphomevalonate to form isopentenyl diphosphate (IPP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoids and sterol synthesis.
Target Involvement

Porokeratosis 7, multiple types (POROK7)
Target Subcellular Location

Cytoplasm.
Target Protein Families

Diphosphomevalonate decarboxylase family
Target Tissue Specificity

Expressed in heart, skeletal muscle, lung, liver, brain, pancreas, kidney and placenta.
Target Synonyms

Diphosphomevalonate decarboxylase; FP17780; MDDase; Mevalonate (diphospho) decarboxylase; Mevalonate (diphospho)decarboxylase; Mevalonate pyrophosphate decarboxylase; MPD; Mvd; MVD1_HUMAN
Target Background

The enzyme mevalonate pyrophosphate decarboxylase catalyzes the conversion of mevalonate pyrophosphate into isopentenyl pyrophosphate in one of the early steps in cholesterol biosynthesis. It decarboxylates and dehydrates its substrate while hydrolyzing ATP.

Rabbit anti-Human MVD Polyclonal Antibody

Specifications

Immunogen Information

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