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The antibody against MVD was raised in rabbit using the Recombinant Human Diphosphomevalonate decarboxylase protein (69-221AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against MVD was raised in rabbit using the Recombinant Human Diphosphomevalonate decarboxylase protein (69-221AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
$299.00
| Cat.No | ADC-05969A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MVD |
| Form | Liquid | Species Reactivity | Human, Rat |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Diphosphomevalonate decarboxylase protein (69-221AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P53602 |
Uniprot Id
P53602
Target Species
Human
Target Name
MVD
Target Full Name
Diphosphomevalonate decarboxylase
Target Function
Catalyzes the ATP dependent decarboxylation of (R)-5-diphosphomevalonate to form isopentenyl diphosphate (IPP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoids and sterol synthesis.
Target Involvement
Porokeratosis 7, multiple types (POROK7)
Target Subcellular Location
Cytoplasm.
Target Protein Families
Diphosphomevalonate decarboxylase family
Target Tissue Specificity
Expressed in heart, skeletal muscle, lung, liver, brain, pancreas, kidney and placenta.
Target Synonyms
Diphosphomevalonate decarboxylase; FP17780; MDDase; Mevalonate (diphospho) decarboxylase; Mevalonate (diphospho)decarboxylase; Mevalonate pyrophosphate decarboxylase; MPD; Mvd; MVD1_HUMAN
Target Background
The enzyme mevalonate pyrophosphate decarboxylase catalyzes the conversion of mevalonate pyrophosphate into isopentenyl pyrophosphate in one of the early steps in cholesterol biosynthesis. It decarboxylates and dehydrates its substrate while hydrolyzing ATP.
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